Protein Info for EX28DRAFT_0154 in Enterobacter asburiae PDN3

Annotation: Uncharacterized protein conserved in bacteria

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 634 TIGR04382: 5-dehydro-2-deoxygluconokinase" amino acids 4 to 329 (326 residues), 428.9 bits, see alignment E=5.7e-133 PF00294: PfkB" amino acids 6 to 321 (316 residues), 151.8 bits, see alignment E=2.8e-48 PF09863: DUF2090" amino acids 324 to 631 (308 residues), 496.3 bits, see alignment E=3.3e-153

Best Hits

KEGG orthology group: K03338, 5-dehydro-2-deoxygluconokinase [EC: 2.7.1.92] (inferred from 96% identity to enc:ECL_03802)

MetaCyc: 53% identical to bifunctional 5-dehydro-2-deoxygluconokinase/5-dehydro-2-deoxyphosphogluconate aldolase (Caulobacter vibrioides NA1000)
5-dehydro-2-deoxyphosphogluconate aldolase. [EC: 4.1.2.29]; 5-dehydro-2-deoxygluconokinase. [EC: 4.1.2.29, 2.7.1.92]

Predicted SEED Role

"5-keto-2-deoxygluconokinase (EC 2.7.1.92) / uncharacterized domain" in subsystem Inositol catabolism (EC 2.7.1.92)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.92 or 4.1.2.29

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (634 amino acids)

>EX28DRAFT_0154 Uncharacterized protein conserved in bacteria (Enterobacter asburiae PDN3)
MEKQFDVICMGRVAVDLYSQQIGARLEDASSFAKYLGGSSGNVAYGTARQGLRSSMLARV
GDEHMGRFLREELNQVGCDTSHLITDKQRLTALVLLGIKDRDTFPLIFYRDNCADMAITA
SDVDESYIASARCLAITGTHLSHPQTREAVLTALGYARRHGVRTVLDIDYRPVLWGLTAL
GDGETRFIAADKVTRELQEVLHLFDVIVGTEEEFHIAGGSTDTLQALEQVRAVSDAALVC
KRGALGCSVYTDAIPPRLDDGLTVTGVRVEVLNVLGAGDAFMSGLLRGYLNDEGWEQACR
YANACGALVVSRHGCAPAMPSKIELDDYLSRAADVPRPDLDSRLNHLHRVTTRRREWPEL
CVMAFDHRSQLEDMAMQCGASLKRIPALKQLILQASREAASRAGLEGKAGLLCDGTFGQD
ALNAITGEGWWIGRPIELPGSRPLEMEHGNIGTQLISWPQEHVVKCLVFFHPEDAHGLRL
EQEQKIAEVYHACCQSGHELLLEVILPATMPRSDELYLRAISRFYNLGIYPDWWKLPPLS
ADGWTALSEIIERRDPHCRGVVILGLDAPAEQLRADFKAAAGQAVVKGFAVGRTLFGDAS
RAWLKHDIDDAQLVARIRDNYLQLIAWWRERGHA