Protein Info for EFB2_03415 in Escherichia fergusonii Becca

Annotation: HTH-type transcriptional repressor GlcR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 PF08220: HTH_DeoR" amino acids 6 to 59 (54 residues), 67.9 bits, see alignment E=5.2e-23 PF00455: DeoRC" amino acids 77 to 232 (156 residues), 161 bits, see alignment E=2.4e-51

Best Hits

Swiss-Prot: 34% identical to Y1009_HAEIN: Uncharacterized HTH-type transcriptional regulator HI_1009 (HI_1009) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 100% identity to ecg:E2348C_0570)

Predicted SEED Role

"Glycerol-3-phosphate regulon repressor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (253 amino acids)

>EFB2_03415 HTH-type transcriptional repressor GlcR (Escherichia fergusonii Becca)
MKGYNRLEQIMDYLKSHNLVTVDELVAVTNASPATIRRDLIKLDEQGVISRTHGGVTLNR
FIPTQPTTHEKMQRSLAEKHAIASAAASMVKAGDSVVLDAGTTMIELARQITHLPLRVIT
SDLHIALFLAEFKQIEVTIIGGRIDDSSQSCIGEHGRKLLQNTWPDMAFLSCNSWDLEKG
ITAPTEEKAALKRDLIAHASRKILLADSSKYGSWSLFNIAHLNELTEIITDSQLDGQTRR
TLASLSTRLIIAD