Protein Info for EFB2_03221 in Escherichia fergusonii Becca

Annotation: Putative prophage major tail sheath protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 390 PF04984: Phage_sheath_1" amino acids 108 to 273 (166 residues), 113.3 bits, see alignment E=1.1e-36 PF17482: Phage_sheath_1C" amino acids 275 to 377 (103 residues), 83.4 bits, see alignment E=1.1e-27

Best Hits

Swiss-Prot: 68% identical to TSP_BPP2: Tail sheath protein (FI) from Escherichia phage P2

KEGG orthology group: K06907, (no description) (inferred from 98% identity to ecg:E2348C_0836)

Predicted SEED Role

"Phage tail sheath monomer"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (390 amino acids)

>EFB2_03221 Putative prophage major tail sheath protein (Escherichia fergusonii Becca)
MAQDYHHGVRVVEVNEGTRSITTVSTAIVGMVCTGDDADAKMFPLNKPVLITDVLTASGK
AGESGTLARSLDAIADQAKPVTVVVRVPQGETEEETTTNIIGAVTAEGKKTGMKALLSAQ
SQLGVKPRILGVPGHDTKAVATELLSVAQSLRGFAYLSAYGCKTVQEAITYRENFSQREG
MLIWPDFTGWDTVLNAEATAYATARALGLRAKIDEQTGWHKSLSNVGVNGVTGISADVFW
DLQDPATDAGLLNQNDVTTLVRKDGFRFWGSRCLSDDPLFAFENYTRTAQVLMDTMAEAH
MWAVDKPLNPSLARDIIEGIRAKMRNLVSQGYLIGGDCWLDESVNDKDTLKAGKLTIDYD
YTPVPPLENLMLRQRITDQYLVNFASQVSA