Protein Info for EFB2_03005 in Escherichia fergusonii Becca

Annotation: IS3 family transposase ISEc16

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 284 transmembrane" amino acids 141 to 159 (19 residues), see Phobius details PF00665: rve" amino acids 122 to 220 (99 residues), 98 bits, see alignment E=5e-32 PF13683: rve_3" amino acids 212 to 275 (64 residues), 40 bits, see alignment E=4.1e-14 PF13333: rve_2" amino acids 227 to 283 (57 residues), 69.5 bits, see alignment E=3.2e-23

Best Hits

Swiss-Prot: 85% identical to INSF5_ECOLI: Transposase InsF for insertion sequence IS3E (insF5) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to ecp:ECP_0283)

Predicted SEED Role

"Mobile element protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (284 amino acids)

>EFB2_03005 IS3 family transposase ISEc16 (Escherichia fergusonii Becca)
MKYVFIENHRAEFSIKAMCRVLRVARSGWYVWLWRRHQMSLRQQFRLTCDAAFHKAFFEA
KQRYGAPRLADEMPEFNIKTIAASLRRQGLRAKASRKFSPVSYRAHGLPVLENLLEQDFS
ASGPNQKWAGDITYLRTDEGWLYLAVVIDLWSRAVIGWSMSLRMTAQLACDALQMALWRR
RRPESVIVHTDRGGQYCSGDYQALLKRHNLRGSMSAKGYCYDNACVESFFHSLKVEYIHG
ERFSSREIMRATVFNYIECDYNRWRRHSACGGLSPEQFENHNLA