Protein Info for EFB2_02552 in Escherichia fergusonii Becca

Annotation: Tellurite resistance protein TehA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 transmembrane" amino acids 7 to 30 (24 residues), see Phobius details amino acids 39 to 64 (26 residues), see Phobius details amino acids 77 to 98 (22 residues), see Phobius details amino acids 104 to 124 (21 residues), see Phobius details amino acids 149 to 179 (31 residues), see Phobius details amino acids 197 to 218 (22 residues), see Phobius details amino acids 230 to 249 (20 residues), see Phobius details amino acids 256 to 275 (20 residues), see Phobius details amino acids 285 to 309 (25 residues), see Phobius details PF03595: SLAC1" amino acids 8 to 305 (298 residues), 148.2 bits, see alignment E=1.6e-47 TIGR00816: C4-dicarboxylate transporter/malic acid transport protein" amino acids 9 to 312 (304 residues), 370.9 bits, see alignment E=2.9e-115

Best Hits

Swiss-Prot: 99% identical to TEHA_ECOLI: Tellurite resistance protein TehA (tehA) from Escherichia coli (strain K12)

KEGG orthology group: K03304, tellurite resistance/dicarboxylate transporter, TDT family (inferred from 99% identity to eco:b1429)

MetaCyc: 99% identical to tellurite resistance protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-539

Predicted SEED Role

"Tellurite resistance protein TehA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (330 amino acids)

>EFB2_02552 Tellurite resistance protein TehA (Escherichia fergusonii Becca)
MQSDKVLNLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMIIWGLLTGAFI
TRLIRFPHSVLAEVRHPVLSSFVSLFPATTMLVAIGFVPWFRPLAVCLFSFGVVVQLAYA
AWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALGYTDAGLVFLGAGVFSWLSLE
PVILQRLRSSGELPTTLRTSLGIQLAPALVACSAWLSVNGGEGDTLAKMLFGYGLLQLLF
MLRLMPWYLSQPFNASFWSFSFGVSALATTGLHLGSGSDNGFFHTLAVPLFIFTNFIIAI
LLIRTFALLMQGKLLVRTERAVLMKAEDKE