Protein Info for EFB2_02427 in Escherichia fergusonii Becca

Annotation: Cryptic outer membrane porin BglH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 557 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF11471: Sugarporin_N" amino acids 30 to 56 (27 residues), 30.7 bits, see alignment (E = 3.1e-11) PF02264: LamB" amino acids 147 to 557 (411 residues), 264.1 bits, see alignment E=4e-82

Best Hits

KEGG orthology group: K10124, carbohydrate-specific outer membrane porin (inferred from 100% identity to ecz:ECS88_1610)

Predicted SEED Role

"Maltoporin (maltose/maltodextrin high-affinity receptor, phage lambda receptor protein)" in subsystem Maltose and Maltodextrin Utilization or Trehalose Uptake and Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (557 amino acids)

>EFB2_02427 Cryptic outer membrane porin BglH (Escherichia fergusonii Becca)
MNIKTLNVSLLSISIITALFPLNAMATKLTIEQRLELLENELSQNKQELKATQNELGVYK
FRLSTLQKSITENKYQSASLAEISATSPVADNIKNENGEQNSFAAAHTINGSQQIAVIES
KGDKTTIESVTLKDISKYIKDDIGFSYQGYFRSGWGTGNHGSPQTYAAGSLGRFGNEMSG
WFDLTLNQRVYNQDGRTANAVVTYDGNVGQQYNDAWFGDSANENIMQFSDIYLTTRGFLP
FAREAEFWVGKHKLPQYEIQMLDWKTLTTDVAAGVGIENWALGVGLFDMSLSRDDVDVYS
RDFTRTSQMNTNSVDVRYRNIPLWDDATLSLMAKYSAPNKTDQQQDNENDDSYFEMKDSW
MLTSVLRQNLQRDTFNEFTLQVANNSYASSFASFSDASNTMAHGRYYYGDHTNGIAWRLI
SQGEMYLTDNIIMANALVYSHGEDVYSYESGAHSDFDSIRTVIRPAWIWNTWNQTGLELG
WFKQQNKTQQGVTLNESAYKTTLWHALKVGESILGSRPEIRFYGTYINILDNELSNFKFN
ENSKNEFMAGIQAEVWW