Protein Info for EFB2_02246 in Escherichia fergusonii Becca

Annotation: Arginine N-succinyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 344 PF04958: AstA" amino acids 1 to 335 (335 residues), 462.3 bits, see alignment E=3.4e-143 TIGR03244: arginine N-succinyltransferase" amino acids 3 to 337 (335 residues), 553.5 bits, see alignment E=1.4e-170 TIGR03243: arginine and ornithine succinyltransferase subunits" amino acids 3 to 337 (335 residues), 510.7 bits, see alignment E=1.5e-157

Best Hits

Swiss-Prot: 100% identical to ASTA_ECOK1: Arginine N-succinyltransferase (astA) from Escherichia coli O1:K1 / APEC

KEGG orthology group: K00673, arginine N-succinyltransferase [EC: 2.3.1.109] (inferred from 100% identity to ecq:ECED1_1949)

MetaCyc: 99% identical to arginine N-succinyltransferase (Escherichia coli K-12 substr. MG1655)
Arginine N-succinyltransferase. [EC: 2.3.1.109]

Predicted SEED Role

"Arginine N-succinyltransferase (EC 2.3.1.109)" in subsystem Arginine and Ornithine Degradation (EC 2.3.1.109)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.109

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (344 amino acids)

>EFB2_02246 Arginine N-succinyltransferase (Escherichia fergusonii Becca)
MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSVRIERAIKTWQGELPKSEQGYVF
VLEDSETGTVAGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSS
ELCTLFLDPKWRKEGNGYLLSKSRFMFMAAFRDKFNDKVVAEMRGVIDEHGYSPFWQSLG
KRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTYFLSQEAQDVIGQVHPQTAPARAVLE
KEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAQGDFPACLVANENYHHF
RVVLVRTDPATERLILTAAQLDVLKCHAGDRVRLVRLCAEEKTA