Protein Info for EFB2_01992 in Escherichia fergusonii Becca

Annotation: Mannosyl-3-phosphoglycerate phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 271 TIGR02463: mannosyl-3-phosphoglycerate phosphatase homolog" amino acids 9 to 232 (224 residues), 329.1 bits, see alignment E=2.1e-102 TIGR01486: mannosyl-3-phosphoglycerate phosphatase family" amino acids 9 to 268 (260 residues), 334.1 bits, see alignment E=7.8e-104 TIGR01484: HAD hydrolase, family IIB" amino acids 9 to 231 (223 residues), 151.8 bits, see alignment E=4.3e-48 PF08282: Hydrolase_3" amino acids 10 to 232 (223 residues), 51.5 bits, see alignment E=1.2e-17 PF05116: S6PP" amino acids 143 to 267 (125 residues), 22.5 bits, see alignment E=7.7e-09

Best Hits

Swiss-Prot: 100% identical to MPGP_ECOL5: Mannosyl-3-phosphoglycerate phosphatase (yedP) from Escherichia coli O6:K15:H31 (strain 536 / UPEC)

KEGG orthology group: K07026, mannosyl-3-phosphoglycerate phosphatase [EC: 3.1.3.70] (inferred from 99% identity to ecg:E2348C_2068)

Predicted SEED Role

"Putative mannosyl-3-phosphoglycerate phosphatase (EC 3.1.3.70)" (EC 3.1.3.70)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.70

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (271 amino acids)

>EFB2_01992 Mannosyl-3-phosphoglycerate phosphatase (Escherichia fergusonii Becca)
MFSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLSRLHEANIPVILCSSKTSAEMLYLQKM
LGLQGLPLIAENGAVIQLAEQWQDIDGFPRIISGISHGEICQVLNTLREKEHFKFTTFDD
VDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDEHMAQFIARLNELGLQFMQGARFWH
VLDASAGKDQAANWIIATYQQLSGRRPTTLGLGDGPNDAPLLEVMDYAVIVKGLNREGVH
LHDEDPARVWRTQREGPEGWREGLDHFFSAR