Protein Info for EFB2_01957 in Escherichia fergusonii Becca

Annotation: DNA-binding protein H-NS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 134 PF22470: Histone_HNS_N" amino acids 1 to 78 (78 residues), 87.1 bits, see alignment E=5.9e-29 PF00816: Histone_HNS" amino acids 95 to 134 (40 residues), 61.3 bits, see alignment E=5.9e-21

Best Hits

Swiss-Prot: 63% identical to HNSP_SALTI: DNA-binding protein H-NS, plasmid (hns) from Salmonella typhi

KEGG orthology group: K03746, DNA-binding protein H-NS (inferred from 100% identity to ecc:c2411)

Predicted SEED Role

"DNA-binding protein H-NS"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (134 amino acids)

>EFB2_01957 DNA-binding protein H-NS (Escherichia fergusonii Becca)
MSEALKALNNIRTLRAQARETDLATLEEMLEKLTTIVEDRREEENSARKEQEERQAKLEA
FRQKLLEDGIDPTELLASVGSSQPKTKSTRAPRPAKYKYTDENGNEQTWTGQGRTPKAIA
AAIEAGKTLEDFAI