Protein Info for EFB2_01746 in Escherichia fergusonii Becca

Annotation: putative fimbrial chaperone YehC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00345: PapD_N" amino acids 19 to 141 (123 residues), 138.9 bits, see alignment E=9.1e-45 PF02753: PapD_C" amino acids 163 to 219 (57 residues), 34.7 bits, see alignment E=1.8e-12

Best Hits

Swiss-Prot: 98% identical to YEHC_ECOLI: Probable fimbrial chaperone YehC (yehC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ecp:ECP_2148)

Predicted SEED Role

"Uncharacterized fimbrial chaperone YehC precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (224 amino acids)

>EFB2_01746 putative fimbrial chaperone YehC (Escherichia fergusonii Becca)
MKGLLALLISSMVLPAHAGIVIYGTRIIYPAEHKEVMVQLMNQGNRSSLMQAWIDDGDTS
LPPEKIQVPFMLTPPVAKIGANSGQQVKIKIMPNKLPTNKESIFYLNVLDIPPNSPEQEG
KNALKFAMQNRIKLFYRPAGIAPVNKVTFKKLLVNRSGNGLVIKNDSANWVTISDVKANN
VKVNYETIMIAPLESQSVNVKSNNANNWHLTIIDDHGNYISDKI