Protein Info for EFB2_01347 in Escherichia fergusonii Becca

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1093 transmembrane" amino acids 1074 to 1092 (19 residues), see Phobius details PF17128: DUF5107" amino acids 39 to 324 (286 residues), 187 bits, see alignment E=1e-58 PF13432: TPR_16" amino acids 499 to 558 (60 residues), 20.6 bits, see alignment 1.3e-07 amino acids 754 to 813 (60 residues), 19.1 bits, see alignment 4e-07

Best Hits

Swiss-Prot: 98% identical to YPHG_ECOLI: Uncharacterized protein YphG (yphG) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to eco:b2549)

Predicted SEED Role

"Uncharacterized protein YphG, TPR-domain containing" in subsystem Unknown sugar utilization (cluster yphABCDEFG)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1093 amino acids)

>EFB2_01347 hypothetical protein (Escherichia fergusonii Becca)
MTPVKVWQERVEIPTYETGPQDIHPMFLENRVYQGSSGAVYPYGVTDTLSEQKTLKSWQA
VWLENDYIKVMILPELGGRVHRAWDKVKQRDFVYHNEVIKPALVGLLGPWISGGIEFNWP
QHHRPTTFMPVDFTLEAHDDGAQTVWVGETEPMHGLQVMTGFTLRPDRAALEIASRVYNG
NATPRHFLWWANPAVKGGEGHQSVFPPDVTAVFDHGKRAVSAFPIATGTYYKVDYSAGVD
ISRYKNVPVPTSYMAEKSQYDFVGAWCHDEDGGLLHVANHHIAPGKKQWSWGHSEFGQAW
DKSLTDNNGPYIELMTGIFADNQPDFTWLDAYEEKRFEQYFLPYHSLGMVQNASRDAVIK
LQRSERGIEWGLYAISPLNGYRLAIREIGKCNALLDDAVALTPATAIQGVLHGINPERLT
IELSDADGNIVLSYHEHQSQALPLPDVAKAPLAAQDITSTDEAWFIGQHLEQYHHASRSP
FDYYLRGVALDPLDYRCNLALAMLEYNRADFPQAVAYATQALKRAHALNKNPQCGQASLI
RASAYERQGQYQQAEEDFWRAVWSGNSKAGGYYGLARLAARNGNFDTGLDFCQQSLRACP
TNQEVLCLHNLLLVLSGRQDNARLQREKLLRDYPLNATLWWLNWFDGRSESALAQWRGLC
QGRDVNALMTAGQLINWGMPALAAEMLNALDCQRTLPLYLQASLLPKAERGELVAKAIDA
FPQFVRFPNTLEEVAALESIEECWFARHLLACFYYNKRSYGKAIALWQRCVEMSPEFADG
WRGLAIHAWNKQHDYELAARYLDNAYQLAPQDARLLFERDLLDKLSGVTPEKRLARLENN
LEIALKRDDMTAELLNLWHLTSQADKAADILATRKFHPWEGGEGKVTSQFILNQLLRAWQ
HLDARQPQQACELLHAALHYPENLSEGRLPGQTDNDIWFWQAVCANAQGDETEATRCLRL
AATGDRTINIHSYYNDQPVDYLFWQGMALRLLGEQHTAQQLFSEMKQWAKEMAKTSIEAD
FFAVSQPDLLSLYSDLQQQHKEKCLMVAMLAAAGLGEVAHYESARAELMAINPAWPKAAL
FTTVMPFIFSYVH