Protein Info for EFB2_00853 in Escherichia fergusonii Becca

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 392 transmembrane" amino acids 240 to 263 (24 residues), see Phobius details TIGR01709: type II secretion system protein L" amino acids 8 to 391 (384 residues), 355.3 bits, see alignment E=2.3e-110 PF05134: T2SSL" amino acids 43 to 197 (155 residues), 67.5 bits, see alignment E=1.2e-22 PF12693: GspL_C" amino acids 234 to 391 (158 residues), 159.9 bits, see alignment E=5e-51

Best Hits

KEGG orthology group: K02461, general secretion pathway protein L (inferred from 100% identity to ect:ECIAI39_3448)

Predicted SEED Role

"General secretion pathway protein L"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (392 amino acids)

>EFB2_00853 hypothetical protein (Escherichia fergusonii Becca)
MSSMLEIYFPLCAADPIRWQRRTPDVEHGIWPDVADEYLQQWLQTDTIRLYIPGEWISVW
QVELPDVPRKQIPTILPALLEEELNQDIDELHFAPLKIDQQLATVAVIHQQHMRNIAQWL
QANGITRATVAPDWMSIPCGFMAGDAQRVICRIDECRGWSAGRALAPVMFRAQLNEQNLP
ISLTVVGIAPEELSAWAGADAERLTVTALPAITTYGESEGNLLTGPWQPRVSYRKQWARW
RVMILPILLILVALAVERGVTLWSVSEQVAQSRTQAEKQFLTLFPEQKRIVNLRSQVTMA
LKKYRPQADDTRLLAELSAIASTLKSASLTDIEMRGFTFDQKRQTLHLQLRAANFASFDK
LRSALAADYVVQQDALQKEGDAVSGGVTLRRK