Protein Info for EFB2_00278 in Escherichia fergusonii Becca

Annotation: Cellulose synthase operon protein C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1157 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13432: TPR_16" amino acids 274 to 336 (63 residues), 28.9 bits, see alignment 6.9e-10 amino acids 356 to 418 (63 residues), 30.6 bits, see alignment 2.1e-10 amino acids 389 to 443 (55 residues), 23.1 bits, see alignment 4.3e-08 PF07719: TPR_2" amino acids 304 to 336 (33 residues), 24.1 bits, see alignment (E = 1.3e-08) PF13181: TPR_8" amino acids 304 to 336 (33 residues), 26.1 bits, see alignment (E = 3.1e-09) PF13176: TPR_7" amino acids 305 to 334 (30 residues), 18.5 bits, see alignment (E = 8.1e-07) PF14559: TPR_19" amino acids 615 to 668 (54 residues), 36.2 bits, see alignment 3.1e-12 PF05420: BCSC_C" amino acids 802 to 1136 (335 residues), 402.1 bits, see alignment E=1e-123

Best Hits

Swiss-Prot: 99% identical to BCSC_ECOLI: Cellulose synthase operon protein C (bcsC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to ecq:ECED1_4208)

Predicted SEED Role

"Cellulose synthase operon protein C"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1157 amino acids)

>EFB2_00278 Cellulose synthase operon protein C (Escherichia fergusonii Becca)
MRKFTLNIFTLSLGLAVMPMVEAAPTAQQQLLEQVRLGEATHREDLVQQSLYRLELIDPN
NPDVIAARFRSLLRQGDIDGAQKQLDRLSQLAPSSNAYKSSRTTMLLSTSDGRQALQQAR
LQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIPARRGEAINQLKRINADTPGN
TGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGASKIWYGQIKDMPVSDASVQALKK
YLSIFSDGDSVAAAQSQLAEQQKQLADPAFRARAQGLAAVDSGMAGKAIPELQQAVRANP
KDSEALGALGQAYSQKGDRANAVANLEKALALDPHNSNNDKWNSLLKVNRYWLAIQQGDA
ALKANNPDPAERLFQQARNVDNTDSYAVLGLGDVAMARKDYPAAERYYQQTLRMDSGNTN
AVRGLANIYRQQSPEKAEAYIASLSASQRRSIDDIERSLQNDRLAQQAEALENQGKWAQA
AALQRQRLALDPGSVWITYRLSQDLWQAGQRSQADTLMRNLAQQKPNDPEQVYAYGLYLS
GHDQDRAALAHINSLPRAQWNSNIQELVNRLQNDQVLETANRLRENGKEAEAEAMLRQQP
PSSRIDLTLADWAQQRRDYTAARAAYQNVLTREPTNADAILGLTEVDIAAGDKAAARSQL
AKLPATDNASLNTQRRVALAQAQLGDTAAAQQTFNKLIPQAKSQPPSMESAMVLRDGAKF
EAQAGDPTQALETYKDAMVASGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYR
QQDLNVTLEHDYWGSSGTGGYSDLKAHTTMLQVDAPYSDGRMFFRSDFVNMNVGSFSTNA
DGKWDDNWGTCTLQDCSGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNVVDVVGGISY
SDDIGPLGYTVNAHRRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDNDEANG
VWASLSGDQLTGKNVEDNWRVRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLG
QGGYYSPQEYLSFAIPVMWRERTENWSWELGASGSWSHSRTKTMPRYPLMNLIPTDWQEE
AARQSNDGGSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLLYVRYSAAGW
QGDMDLPPQPLIPYADW