Protein Info for EFB2_00268 in Escherichia fergusonii Becca

Annotation: Inner membrane transport protein YhjV

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 46 to 64 (19 residues), see Phobius details amino acids 94 to 118 (25 residues), see Phobius details amino acids 138 to 155 (18 residues), see Phobius details amino acids 167 to 185 (19 residues), see Phobius details amino acids 204 to 226 (23 residues), see Phobius details amino acids 247 to 267 (21 residues), see Phobius details amino acids 294 to 318 (25 residues), see Phobius details amino acids 339 to 362 (24 residues), see Phobius details amino acids 368 to 389 (22 residues), see Phobius details amino acids 401 to 420 (20 residues), see Phobius details

Best Hits

Swiss-Prot: 98% identical to YHJV_ECOLI: Inner membrane transport protein YhjV (yhjV) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ecq:ECED1_4218)

MetaCyc: 45% identical to L-cysteine importer (Escherichia coli K-12 substr. MG1655)
RXN-23966

Predicted SEED Role

"Serine transporter" in subsystem Glycine and Serine Utilization or Pyruvate Alanine Serine Interconversions or Threonine anaerobic catabolism gene cluster

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (423 amino acids)

>EFB2_00268 Inner membrane transport protein YhjV (Escherichia fergusonii Becca)
MQHNTLPKHDQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGLKGIWVFITAAIIAYPA
TWVVQDIYLKTLSESDSCNDYTDIISHYLGKNWGIFLGVIYFLMIIHGIFIYSLSVVFDS
ASYLKTFGLTDADLSQSLFYKVAIFAVLVAIASGGERLLFKISGPMVVVKVGIIVVFGFA
MIPHWNFANITAFPQASDFFRDVLLTIPFCFFSAVFIQVLNPMNIAYRKREADKVLATRL
ALRTHRISYITLIAVILFFAFSFTFSISHEEAVSAFEQNISALALAAQVIPGHIIHITST
VLNIFAVLTAFFGIYLGFHEAIKGIILNLLSRIIDTRKINSLVLTLAICTFIVITLTIWV
SFRVSVLVFFQLGSPLYGIVSCLIPFFLISKVSQLEKLRGFKAWMILLYGILLCLSPLLK
LIE