Protein Info for EFB2_00208 in Escherichia fergusonii Becca

Annotation: Autotransporter adhesin UpaG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1732 transmembrane" amino acids 35 to 53 (19 residues), see Phobius details PF13018: ESPR" amino acids 1 to 48 (48 residues), 57.8 bits, see alignment (E = 2.9e-19) PF05658: YadA_head" amino acids 102 to 123 (22 residues), 11 bits, see alignment (E = 0.00012) amino acids 111 to 137 (27 residues), 24.6 bits, see alignment (E = 6.3e-09) amino acids 126 to 151 (26 residues), 25.5 bits, see alignment (E = 3.3e-09) amino acids 157 to 179 (23 residues), 14.9 bits, see alignment (E = 7e-06) amino acids 181 to 205 (25 residues), 12 bits, see alignment (E = 5.8e-05) amino acids 209 to 235 (27 residues), 23.6 bits, see alignment (E = 1.3e-08) amino acids 237 to 263 (27 residues), 19.7 bits, see alignment (E = 2.1e-07) amino acids 267 to 290 (24 residues), 26.4 bits, see alignment (E = 1.7e-09) amino acids 278 to 304 (27 residues), 24.5 bits, see alignment (E = 6.9e-09) amino acids 292 to 317 (26 residues), 20.4 bits, see alignment (E = 1.3e-07) amino acids 309 to 331 (23 residues), 21.3 bits, see alignment (E = 6.9e-08) amino acids 335 to 360 (26 residues), 29.1 bits, see alignment (E = 2.4e-10) amino acids 362 to 388 (27 residues), 23.3 bits, see alignment (E = 1.6e-08) amino acids 1201 to 1227 (27 residues), 29.5 bits, see alignment (E = 1.8e-10) amino acids 1215 to 1241 (27 residues), 32.9 bits, see alignment (E = 1.6e-11) amino acids 1229 to 1255 (27 residues), 11.8 bits, see alignment (E = 6.4e-05) amino acids 1375 to 1401 (27 residues), 19.5 bits, see alignment (E = 2.6e-07) amino acids 1508 to 1525 (18 residues), 14.1 bits, see alignment (E = 1.3e-05) amino acids 1513 to 1539 (27 residues), 30.3 bits, see alignment (E = 1e-10) amino acids 1527 to 1552 (26 residues), 17.8 bits, see alignment (E = 8.3e-07) PF05662: YadA_stalk" amino acids 392 to 433 (42 residues), 31.2 bits, see alignment (E = 6.1e-11) amino acids 486 to 514 (29 residues), 32.7 bits, see alignment (E = 2e-11) amino acids 533 to 577 (45 residues), 37.5 bits, see alignment (E = 6.4e-13) amino acids 611 to 655 (45 residues), 40.6 bits, see alignment (E = 7.1e-14) amino acids 689 to 733 (45 residues), 40.6 bits, see alignment (E = 7.1e-14) amino acids 767 to 811 (45 residues), 46.5 bits, see alignment (E = 9.6e-16) amino acids 838 to 880 (43 residues), 34.1 bits, see alignment (E = 7.6e-12) amino acids 939 to 979 (41 residues), 22.8 bits, see alignment (E = 2.6e-08) amino acids 1039 to 1079 (41 residues), 30.2 bits, see alignment (E = 1.3e-10) amino acids 1129 to 1172 (44 residues), 40 bits, see alignment (E = 1.1e-13) amino acids 1300 to 1339 (40 residues), 34.2 bits, see alignment (E = 6.9e-12) amino acids 1436 to 1477 (42 residues), 41.7 bits, see alignment (E = 3e-14) amino acids 1557 to 1580 (24 residues), 43.3 bits, see alignment (E = 1e-14) amino acids 1610 to 1642 (33 residues), 32.9 bits, see alignment (E = 1.7e-11) PF03895: YadA_anchor" amino acids 1672 to 1732 (61 residues), 70.7 bits, see alignment (E = 2.2e-23)

Best Hits

Predicted SEED Role

"FIG00638466: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1732 amino acids)

>EFB2_00208 Autotransporter adhesin UpaG (Escherichia fergusonii Becca)
MNKIFKVIWNPATGSYTVASETAKSRGKKSGRSKLLISALVAGGLLSSFSVWANAGNDDG
QGIGTGTGWVAIGESAKATAYTDSNGASTAVGYKSNAQGVWSSAIGALTSALGDSSMAFG
VNAVSTGQRSIAMGASSSSLGEYSIALGRYASSGGMFSLAQGDRSNAAGLNATAVGSNSN
AAGAKAIALGNAAKATEIMSIALGDTANASKEYSMALGVSSAASAANAIAVGRNSAAAGV
DSLALGRLSVASAANAIAMGAESEAAENATAIGNNAHAKGVNSIAMGSGSIADKVNTIAL
GNGSQSLADNAIAIGQGNKANGTDAIALGNASLSSGLNSIALGKTSVVTGDNSLALGSNT
NANGINSVALGADSIADQDNSVSVGSSSLQRKIVNVKNGAIKADSHDAINGSQLYAISDS
IAKRLGGGSSVNPDDGTVNAPTYNLKNGNKNNVGSALTVLDENTLQWDQIKGKYSAVHGS
STTSVITDVANGTISAASKDAVNGSQLYDLQQDALLWNGTAFSAAHGTEATSKITNVTAG
NLTASSTDAVNGSQLKTTNDNVTTNTTNIATNTTNITNLTDAVNGLGDDSLLWNKTAGAF
SAAHGTDATSKITNVKAGDLTAGSTDAVNGSQLKTTNDNVTTNTTNIATNTTNITNLTDA
VNGLGDDSLLWNKTAGAFSAAHGTDATSKITNVKAGDLTAGSTDAVNGSQLKTTNDNVTT
NTTNIATNTTNITNLTDAVNGLGDDSLLWNKTAGAFSAAHGTDATSKITNVKAGDLTAGS
TDAVNGSQLKTTNDNVSTNTTNITNLTDSVGDLKDDSLLWNKAAGAFSAAHGTEATSKIT
NLLAGKISSNSTDAINGSQLYGVADSFTSYLGGGADISDTGVLSGPTYTIGGTDYTNVGD
ALAAINTSFSTSLGDALLWDATAGKFSAKHGINNAPSVITDVANGAVSSTSSDAINGSQL
YGVSDYIADALGGNAVVNTDGSITTPTYAIAGGSYNNVGDALEAIDTTLDDALLWDTTAN
GGNGAFSAAHGKDKTASVITNVANGAVSATSSDAINGSQLYSTNKYIADALGGDAEVNAD
GTITAPTYTIANTDYNNVGEALDALDNNALLWDEDAGAYNASHDGNASKITNVAAGDLST
TSTDAVNGSQLNATNILVTQNSQMINQLAGNTSETYIEDNGAGINYVRTNDTGLTFTDAS
AAGIGSTAVGYNTVAKGDSSVAMGYNSFAKGDSSVAIGQGSYSGVDTGIALGSSSVSSRV
IVKGSRNTSVSEEGVVIGYDTTDGELLGALSIGDDGKYRQIINVADGSEAHDAVTVRQLQ
NAIGAVATTPTKYYHANSTAEDSLAVGEDSLAMGAKTIVNGNAGIGIGLNTLVLADAING
IAIGSNARANHADSIAMGNGSQTTRGAQTNYTAYNMDAPQNSVGEFSVGSEDGQRQITNV
AAGSADTDAVNVGQLKVTDAQVSQNTQSITNLNTQVTNLDTRVTNIENGIGDIVTTGSTK
YFKTNTDGADANAQGKDSVAIGSGSIAAADNSVALGTGSVANEENTISVGSSTNQRRITN
VAAGVNATDAVNVSQLKSSEAGGVRYDTKADGSIDYSNITLGGGNGGTTRISNVSAGVNN
NDAVNYAQLKQSVQETKQYTDQRMVEMDNKLSKTESKLSGGIASAMAMTGLPQAYTPGAS
MASIGGGTYNGESAVALGVSMVSANGRWVYKLQGSTNSQGEYSAALGAGIQW