Protein Info for EFB2_00201 in Escherichia fergusonii Becca

Annotation: Protein-export protein SecB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 155 PF02556: SecB" amino acids 5 to 144 (140 residues), 196.3 bits, see alignment E=1.1e-62 TIGR00809: protein-export chaperone SecB" amino acids 5 to 147 (143 residues), 236.9 bits, see alignment E=3.2e-75

Best Hits

Swiss-Prot: 100% identical to SECB_ECO27: Protein-export protein SecB (secB) from Escherichia coli O127:H6 (strain E2348/69 / EPEC)

KEGG orthology group: K03071, preprotein translocase subunit SecB (inferred from 99% identity to eco:b3609)

Predicted SEED Role

"Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (155 amino acids)

>EFB2_00201 Protein-export protein SecB (Escherichia fergusonii Becca)
MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDLDTASTQLADDVYEVVL
RVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYCPNILFPYARECITSMVSR
GTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA