Protein Info for ECD_04005 in Escherichia coli BL21

Annotation: putative transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.

Best Hits

Swiss-Prot: 100% identical to YJDC_ECOLI: HTH-type transcriptional regulator YjdC (yjdC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to eco:b4135)

Predicted SEED Role

"Transcriptional regulator, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (191 amino acids)

>ECD_04005 putative transcriptional regulator (Escherichia coli BL21)
MQREDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPDKEAILYDALRYLSQQI
DVWRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIAACTFYPDPGHPIHQLADQ
QKSAAYDFTHELLTTLEVDDPAMVAKQMELVLEGCLSRMLVNRSQADVDTAHRLAEDILR
FARCRQGGALT