Protein Info for ECD_03958 in Escherichia coli BL21

Annotation: D-allose ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 transmembrane" amino acids 23 to 48 (26 residues), see Phobius details amino acids 61 to 93 (33 residues), see Phobius details amino acids 105 to 127 (23 residues), see Phobius details amino acids 134 to 153 (20 residues), see Phobius details amino acids 168 to 193 (26 residues), see Phobius details amino acids 222 to 242 (21 residues), see Phobius details amino acids 252 to 273 (22 residues), see Phobius details amino acids 279 to 298 (20 residues), see Phobius details amino acids 304 to 324 (21 residues), see Phobius details PF02653: BPD_transp_2" amino acids 52 to 318 (267 residues), 186.9 bits, see alignment E=2.2e-59

Best Hits

Swiss-Prot: 100% identical to ALSC_ECOLI: D-allose transport system permease protein AlsC (alsC) from Escherichia coli (strain K12)

KEGG orthology group: K10550, D-allose transport system permease protein (inferred from 100% identity to eco:b4086)

MetaCyc: 100% identical to D-allose ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-42-RXN [EC: 7.5.2.8]

Predicted SEED Role

"D-allose ABC transporter, permease component" in subsystem D-allose utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>ECD_03958 D-allose ABC transporter permease (Escherichia coli BL21)
MGFTTRVKSEASEKKPFNFALFWDKYGTFFILAIIVAIFGSLSPEYFLTTNNITQIFVQS
SVTVLIGMGEFFAILVAGIDLSVGAILALSGMVTAKLMLAGVDPFLAAMIGGVLVGGALG
AINGCLVNWTGLHPFIITLGTNAIFRGITLVISDANSVYGFSFDFVNFFAASVIGIPVPV
IFSLIVALILWFLTTRMRLGRNIYALGGNKNSAFYSGIDVKFHILVVFIISGVCAGLAGV
VSTARLGAAEPLAGMGFETYAIASAIIGGTSFFGGKGRIFSVVIGGLIIGTINNGLNILQ
VQTYYQLVVMGGLIIAAVALDRLISK