Protein Info for ECD_03603 in Escherichia coli BL21

Annotation: putative xylanase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02922: CBM_48
  • amino acids 45 to 103 (59 residues), 30.3 bits, E=4.5e-11
• PF00756: Esterase
  • amino acids 150 to 340 (191 residues), 64.3 bits, E=1.6e-21

Best Hits

Swiss-Prot: 99% identical to YIEL_ECOLI: Uncharacterized protein YieL (yieL) from Escherichia coli (strain K12)

KEGG orthology group: K07214, enterochelin esterase and related enzymes (inferred from 99% identity to eco:b3719)

Predicted SEED Role

"Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8)" in subsystem D-Galacturonate and D-Glucuronate Utilization or Xylose utilization (EC 3.2.1.8)

MetaCyc Pathways

• (1,4)-β-D-xylan degradation (1/2 steps found)
• cellulose and hemicellulose degradation (cellulolosome) (1/3 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.8

Protein Sequence (389 amino acids)

>ECD_03603 putative xylanase (Escherichia coli BL21)
MNIKIAALTLAIASGISAQWAIAADMPASPAPTIPVKQYVTQVNADNSVTFRYFAPGAKN
VSVVVGVPVPDNIHPMTKDEAGVWSWRTPILKGNLYEYFFNVDGVRSIDTGTAMTKPQRQ
VNSSMILVPGSYLDTRSVAHGDLIAITYHSNALQFERQMYVWTPPGYTGMGEPLPVLYFY
HGFGDTGRSAIDQGRIPQIMDNLLAEGKIKPMLVVIPDTETDAKGIIPEDFVPQERRKVF
YPLNAKAADRELMNDIIPLISKRFNVRKDADGRALAGLSQGGYQALVSGMNHLESFGWLA
TFSGVTTTTVPDEGVAARLNDPAAINQQLRNFTVVVGDKDVVTGKDIAGLKTELEQKKIK
FDYQEYPGLNHEMDVWRPAYAAFVQKLFK