Protein Info for ECD_03550 in Escherichia coli BL21

Annotation: hexose phosphate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 transmembrane" amino acids 27 to 45 (19 residues), see Phobius details amino acids 62 to 85 (24 residues), see Phobius details amino acids 97 to 116 (20 residues), see Phobius details amino acids 122 to 143 (22 residues), see Phobius details amino acids 160 to 185 (26 residues), see Phobius details amino acids 191 to 210 (20 residues), see Phobius details amino acids 260 to 278 (19 residues), see Phobius details amino acids 298 to 318 (21 residues), see Phobius details amino acids 327 to 345 (19 residues), see Phobius details amino acids 352 to 379 (28 residues), see Phobius details amino acids 392 to 411 (20 residues), see Phobius details amino acids 423 to 446 (24 residues), see Phobius details PF07690: MFS_1" amino acids 35 to 397 (363 residues), 124.2 bits, see alignment E=3e-40 TIGR00881: phosphoglycerate transporter family protein" amino acids 36 to 426 (391 residues), 481.3 bits, see alignment E=1.1e-148

Best Hits

Swiss-Prot: 100% identical to UHPT_ECOLI: Hexose-6-phosphate:phosphate antiporter (uhpT) from Escherichia coli (strain K12)

KEGG orthology group: K07784, MFS transporter, OPA family, hexose phosphate transport protein UhpT (inferred from 100% identity to eco:b3666)

MetaCyc: 100% identical to hexose-6-phosphate:phosphate antiporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-33; TRANS-RXN0-501; TRANS-RXN0-502; TRANS-RXN0-534

Predicted SEED Role

"Hexose phosphate transport protein UhpT" in subsystem Hexose Phosphate Uptake System

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (463 amino acids)

>ECD_03550 hexose phosphate transporter (Escherichia coli BL21)
MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYLIRKNFNIAQNDMISTY
GLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAICMLGFSASMGSGS
VSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTFLGFWNISHNLGGAGAAGVAL
FGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPESYGLGKAEELFGEEISEEDKET
ESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRIGIDQWSTVYAFQELKLSKAVAIQG
FTLFEAGALVGTLLWGWLSDLANGRRGLVACIALALIIATLGVYQHASNEYIYLASLFAL
GFLVFGPQLLIGVAAVGFVPKKAIGAADGIKGTFAYLIGDSFAKLGLGMIADGTPVFGLT
GWAGTFAALDIAAIGCICLMAIVAVMEERKIRREKKIQQLTVA