Protein Info for ECD_02941 in Escherichia coli BL21

Annotation: fused signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 506 transmembrane" amino acids 168 to 202 (35 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 20 to 114 (95 residues), 43.9 bits, see alignment E=1.2e-15 PF00989: PAS" amino acids 21 to 111 (91 residues), 30.1 bits, see alignment E=1.1e-10 PF13426: PAS_9" amino acids 21 to 107 (87 residues), 37 bits, see alignment E=8.6e-13 PF08447: PAS_3" amino acids 31 to 113 (83 residues), 65.2 bits, see alignment E=1.3e-21 PF00672: HAMP" amino acids 206 to 248 (43 residues), 20.1 bits, see alignment 1.7e-07 PF00015: MCPsignal" amino acids 319 to 473 (155 residues), 159.2 bits, see alignment E=2.4e-50

Best Hits

Swiss-Prot: 100% identical to AER_ECOLI: Aerotaxis receptor (aer) from Escherichia coli (strain K12)

KEGG orthology group: K03776, aerotaxis receptor (inferred from 100% identity to eco:b3072)

Predicted SEED Role

"Aerotaxis sensor receptor protein" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (506 amino acids)

>ECD_02941 fused signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component (Escherichia coli BL21)
MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYTLQELQGQPHNMVRHPD
MPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATD
EEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLPLRWRARGVMTLMFILLAAML
WFVAAPVVTYILCALVVLLASACFEWQIVRPIENVAHQALKVATGERNSVEHLNRSDELG
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMN
QMAASVKQNSATASAADKLSITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLIND
IAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASADKVQS
GSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAEL
VEESAQVSAMVKHRASRLEDAVTVLH