Protein Info for ECD_02818 in Escherichia coli BL21

Annotation: Capsule polysaccharide export protein KpsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 675 PF05159: Capsule_synth" amino acids 37 to 299 (263 residues), 189.7 bits, see alignment E=4.4e-60 amino acids 367 to 457 (91 residues), 50.1 bits, see alignment E=1.4e-17 amino acids 471 to 620 (150 residues), 105.3 bits, see alignment E=2.3e-34

Best Hits

Swiss-Prot: 97% identical to KPSC5_ECOLX: Capsule polysaccharide export protein KpsC (kpsC) from Escherichia coli

KEGG orthology group: K07266, capsular polysaccharide export protein (inferred from 100% identity to ebr:ECB_02818)

Predicted SEED Role

"Capsular polysaccharide export system protein KpsC" in subsystem Rhamnose containing glycans

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (675 amino acids)

>ECD_02818 Capsule polysaccharide export protein KpsC (Escherichia coli BL21)
MIGIFSSGIWRIPHLEKFLAQPCQKLSLLRPVPQEVDAIAVWGHRPSAAKPVAIAKAAGK
PVIRLEDGFVRSLDLGVNGEPPLSLVVDDCGIYYDASKPSALEKLVKDKAGNTALISQAR
EAMHTIVTGDLSKYNLAPAFVADESERSDIVLVVDQTFNDMSVTYGNAGPHEFAAMLEAA
MAENPQAEIWVKVHPDVLEGKKTGYFADLCATQRVRLIAENVSPQSLLRHVSRVYVVTSQ
YGFEALLAGKPVTCFGQPWYAGWGLTDDRHPQSALLSARRGSATLEELFAAAYLRYCRYI
DLQTGEVSDLFTVLQWLQLQRRHLQQRNGYLWAPGLTLWKSAILKPFLQTATNRLSFSRR
CTAASACVVWGVKGEQQWRAEAQRKSLPLWRMEDGFLRSSGLGSDLLPPLSLVLDKRGIY
YDATRPSDLEVLINHSQLTLAQQMRAEKLRQRLVESKLSKYNLGADFSLPAEAKDKKIIL
VPGQVEDDASIKTGTVSIKSNLELLRTVRERNPHAYIIYKPHPDVLVGNRKGNIPAKLIA
ELADYQALDADIIQCIQRADEVHTMTSLSGFEALLHGKQVHCYGLPFYAGWGLTADEHHC
PRRERRLTIADLIYQALIVYPTYIHPIRLQPITVEEAAEYLIQTPRKPMFITRKKAGRVI
RYYRKLIMFCKVRFG