Protein Info for ECD_00924 in Escherichia coli BL21

Annotation: envelope biogenesis factor; DUF218 superfamily protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 259 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 39 to 59 (21 residues), see Phobius details PF02698: DUF218" amino acids 80 to 224 (145 residues), 97.3 bits, see alignment E=3.5e-32

Best Hits

Swiss-Prot: 100% identical to ELYC_ECO57: Envelope biogenesis factor ElyC (elyC) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 100% identity to eco:b0920)

Predicted SEED Role

"Membrane Protein Functionally coupled to the MukBEF Chromosome Partitioning Mechanism" in subsystem MukBEF Chromosome Condensation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (259 amino acids)

>ECD_00924 envelope biogenesis factor; DUF218 superfamily protein (Escherichia coli BL21)
MLFTLKKVIGNMLLPLPLMLLIIGAGLALLWFSRFQKTGKIFISIGWLALLLLSLQPVAD
RLLRPIESTYPTWNNSQKVDYIVVLGGGYTWNPQWAPSSNLINNSLPRLNEGIRLWRENP
GSKLIFTGGVAKTNTVSTAEVGARVAQSLGVPREQIITLDLPKDTEEEAAAVKQAIGDAP
FLLVTSASHLPRAMIFFQQEGLNPLPAPANQLAIDSPLNPWERAIPSPVWLMHSDRVGYE
TLGRIWQWLKGSSGEPRQE