Protein Info for ECD_00857 in Escherichia coli BL21

Annotation: ribosomal protein S6 modification protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 PF18030: Rimk_N" amino acids 1 to 94 (94 residues), 136.8 bits, see alignment E=7.3e-44 TIGR00768: alpha-L-glutamate ligase, RimK family" amino acids 2 to 286 (285 residues), 325.4 bits, see alignment E=1.5e-101 PF08443: RimK" amino acids 97 to 286 (190 residues), 284.2 bits, see alignment E=1.3e-88 PF02655: ATP-grasp_3" amino acids 97 to 263 (167 residues), 34.9 bits, see alignment E=4.8e-12 PF02955: GSH-S_ATP" amino acids 115 to 265 (151 residues), 61.7 bits, see alignment E=1.9e-20 PF07478: Dala_Dala_lig_C" amino acids 132 to 267 (136 residues), 25.4 bits, see alignment E=2.8e-09

Best Hits

Swiss-Prot: 100% identical to RIMK_ECO8A: Ribosomal protein S6--L-glutamate ligase (rimK) from Escherichia coli O8 (strain IAI1)

KEGG orthology group: K05844, ribosomal protein S6 modification protein (inferred from 100% identity to eco:b0852)

MetaCyc: 100% identical to ribosomal protein S6 modification protein (Escherichia coli K-12 substr. MG1655)
6.3.2.-

Predicted SEED Role

"Ribosomal protein S6 glutaminyl transferase" in subsystem Ribosome biogenesis bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (300 amino acids)

>ECD_00857 ribosomal protein S6 modification protein (Escherichia coli BL21)
MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDA
VIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIA
HSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYI
KEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTM
ALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG