Protein Info for ECD_00831 in Escherichia coli BL21
Annotation: retron EC86 RNA-directed DNA polymerase-like protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to RT86_ECOLX: RNA-directed DNA polymerase from retron EC86 from Escherichia coli
KEGG orthology group: None (inferred from 100% identity to ebr:ECB_00831)Predicted SEED Role
"Retron-type RNA-directed DNA polymerase (EC 2.7.7.49)" (EC 2.7.7.49)
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.7.7.49
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (320 amino acids)
>ECD_00831 retron EC86 RNA-directed DNA polymerase-like protein (Escherichia coli BL21) MKSAEYLNTFRLRNLGLPVMNNLHDMSKATRISVETLRLLIYTADFRYRIYTVEKKGPEK RMRTIYQPSRELKALQGWVLRNILDKLSSSPFSIGFEKHQSILNNATPHIGANFILNIDL EDFFPSLTANKVFGVFHSLGYNRLISSVLTKICCYKNLLPQGAPSSPKLANLICSKLDYR IQGYAGSRGLIYTRYADDLTLSAQSMKKVVKARDFLFSIIPSEGLVINSKKTCISGPRSQ RKVTGLVISQEKVGIGREKYKEIRAKIHHIFCGKSSEIEHVRGWLSFILSVDSKSHRRLI TYISKLEKKYGKNPLNKAKT