Protein Info for ECD_00779 in Escherichia coli BL21

Annotation: Fe-binding and storage protein; stress-inducible DNA-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 167 PF00210: Ferritin" amino acids 31 to 166 (136 residues), 80.3 bits, see alignment E=6.7e-27

Best Hits

Swiss-Prot: 100% identical to DPS_ECOHS: DNA protection during starvation protein (dps) from Escherichia coli O9:H4 (strain HS)

KEGG orthology group: K04047, starvation-inducible DNA-binding protein (inferred from 100% identity to eco:b0812)

Predicted SEED Role

"Non-specific DNA-binding protein Dps / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1)" in subsystem Oxidative stress (EC 1.16.3.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.16.3.1

Use Curated BLAST to search for 1.16.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (167 amino acids)

>ECD_00779 Fe-binding and storage protein; stress-inducible DNA-binding protein (Escherichia coli BL21)
MSTAKLVKSKATNLLYTRNDVSDSEKKATVELLNRQVIQFIDLSLITKQAHWNMRGANFI
AVHEMLDGFRTALIDHLDTMAERAVQLGGVALGTTQVINSKTPLKSYPLDIHNVQDHLKE
LADRYAIVANDVRKAIGEAKDDDTADILTAASRDLDKFLWFIESNIE