Protein Info for ECD_00689 in Escherichia coli BL21

Annotation: transcriptional repressor for the mannosyl-D-glycerate catabolic operon

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 240 PF00392: GntR" amino acids 6 to 69 (64 residues), 85.5 bits, see alignment E=1.6e-28 PF07702: UTRA" amino acids 91 to 229 (139 residues), 128.4 bits, see alignment E=1.8e-41

Best Hits

Swiss-Prot: 99% identical to MNGR_ECOLI: Mannosyl-D-glycerate transport/metabolism system repressor MngR (mngR) from Escherichia coli (strain K12)

KEGG orthology group: K11922, GntR family transcriptional regulator, mannosyl-D-glycerate transport/metabolism system repressor (inferred from 99% identity to eco:b0730)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (240 amino acids)

>ECD_00689 transcriptional repressor for the mannosyl-D-glycerate catabolic operon (Escherichia coli BL21)
MGHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILE
SIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVDTHSEVLIFEVIPADDFLQQQLQITAQ
DRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENSKYHFIEEVKKMVIERSEQEI
IPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEYSRNAFNTDDYKFTLIAQRKSSR