Protein Info for ECD_00067 in Escherichia coli BL21

Annotation: DedA family inner membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 transmembrane" amino acids 12 to 37 (26 residues), see Phobius details amino acids 56 to 79 (24 residues), see Phobius details amino acids 145 to 166 (22 residues), see Phobius details amino acids 177 to 196 (20 residues), see Phobius details amino acids 217 to 237 (21 residues), see Phobius details PF09335: VTT_dom" amino acids 36 to 159 (124 residues), 72.9 bits, see alignment E=1.7e-24

Best Hits

Swiss-Prot: 99% identical to YABI_ECOLI: Inner membrane protein YabI (yabI) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to eco:b0065)

Predicted SEED Role

"DedA family inner membrane protein YabI"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (254 amino acids)

>ECD_00067 DedA family inner membrane protein (Escherichia coli BL21)
MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAGLGALIGSGELSFWHAW
LAGIVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTEHALHQHSMFTILVGRFVG
PTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGILAGAAIDIPAGMQSGEFKWL
LLATAVFVWVGGWLCWRLWRSGKATDRLSHYLSRGRLLWLTPLISAIGVVALVVLIRHPL
MPVYIDILRKVVGV