Protein Info for ECD_00065 in Escherichia coli BL21

Annotation: L-ribulokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 566 TIGR01234: ribulokinase" amino acids 2 to 552 (551 residues), 937.9 bits, see alignment E=9.6e-287 PF02782: FGGY_C" amino acids 291 to 501 (211 residues), 142.4 bits, see alignment E=1.7e-45

Best Hits

Swiss-Prot: 100% identical to ARAB_ECOLC: Ribulokinase (araB) from Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)

KEGG orthology group: K00853, L-ribulokinase [EC: 2.7.1.16] (inferred from 99% identity to eco:b0063)

MetaCyc: 99% identical to ribulokinase (Escherichia coli K-12 substr. MG1655)
Ribulokinase. [EC: 2.7.1.16]

Predicted SEED Role

"Ribulokinase (EC 2.7.1.16)" in subsystem L-Arabinose utilization (EC 2.7.1.16)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (566 amino acids)

>ECD_00065 L-ribulokinase (Escherichia coli BL21)
MAIAIGLDFGSDSVRALAVDCASGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIES
MEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWK
DHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIEL
CDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFT
DTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDI
LIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLSWPLEQLAAQH
PELKAQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRSPNANQRLKGVITDLNLA
TDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPL
QIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQ
QWAMSAEQHYLPTSAPAQAAQAVATL