Protein Info for DZA65_RS22655 in Dickeya dianthicola ME23

Annotation: MBL fold metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 257 PF13483: Lactamase_B_3" amino acids 3 to 213 (211 residues), 26.8 bits, see alignment E=7.1e-10 PF12706: Lactamase_B_2" amino acids 19 to 220 (202 residues), 46.7 bits, see alignment E=4.6e-16 PF00753: Lactamase_B" amino acids 60 to 185 (126 residues), 27.7 bits, see alignment E=3.8e-10

Best Hits

Swiss-Prot: 51% identical to YDDR_BACSU: UPF0173 protein YddR (yddR) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 93% identity to dze:Dd1591_4235)

Predicted SEED Role

"Beta-lactamase-like"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385Y4P2 at UniProt or InterPro

Protein Sequence (257 amino acids)

>DZA65_RS22655 MBL fold metallo-hydrolase (Dickeya dianthicola ME23)
MNITQIRNATLKISFAGKTFLIDPMLAEKGAYPGFEGTLNSHLRNPLVDLPVTLESLFAG
VDAVIVTHTHLDHWDDVAAARLPKSLPIFTQHEHDHEMIRAAGFGDVRLLNGLSAFGDIT
LSKTPGQHGSDAIMEILGDRLGEVCGVVLRHPQEKTLYLAGDTVWNAEVAENLRSYAPEV
IVLNCGDAQVVGLGSIIMNQQDVLSVAQHAPSATLIASHMEAVNHSALSREALADFVQQH
GVSHRVLIPADGESCML