Protein Info for DZA65_RS22465 in Dickeya dianthicola ME23

Annotation: acyl-CoA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 PF00501: AMP-binding" amino acids 129 to 306 (178 residues), 45.1 bits, see alignment E=3.2e-16

Best Hits

KEGG orthology group: None (inferred from 87% identity to ddc:Dd586_4171)

Predicted SEED Role

"FIGfam138462: Acyl-CoA synthetase, AMP-(fatty) acid ligase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385Y3D8 at UniProt or InterPro

Protein Sequence (457 amino acids)

>DZA65_RS22465 acyl-CoA synthetase (Dickeya dianthicola ME23)
MNNVTARSLNDWLTHDETSIARLVATNGKQDFTLTMMRYQVMSLCRQLMSCGESRWALCF
EDSYLFTVALLAALHAGKTPVIYGHCRESVLREQSNEFDGLLTDNRMTLACRCLYLATDD
VLHGDSHQIENVLPPVPDDACLILFTSGSTGKPRQIHKPIRCMDEEARWLARLWGERLRD
CHVMASVTHQHMYGLTFRIWLPMSLGLSFDSRQVLYSEQLAAHSSDRRYAFISSPAFLRR
IDHSLQAPLCELIVSAGGVLPWPCAQSAQQWLGSAVDEIYGSTETGVMGWRSRQDEQTVW
QPFPGVSFQGDDDGSWRARSALIPQPEGMKLDDKLAFDERGCFQLCGRHDRIVKIEDKRI
SLSEIERRLLSLPEIDDAVALQVTRQDRSGIGVVLVLKSPAVTAGLPALKRQWRHELHKW
LEPVAMPRFWRIVDAIPLNSQSKRAWPQIQELFHAAG