Protein Info for DZA65_RS22415 in Dickeya dianthicola ME23

Annotation: right-handed parallel beta-helix repeat-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 734 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details

Best Hits

Swiss-Prot: 91% identical to PLYX_DICCH: Pectate disaccharide-lyase (pelX) from Dickeya chrysanthemi

KEGG orthology group: None (inferred from 95% identity to ddd:Dda3937_00143)

Predicted SEED Role

"Exopolygalacturonate lyase (EC 4.2.2.9)" in subsystem D-Galacturonate and D-Glucuronate Utilization (EC 4.2.2.9)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.2.2.9

Use Curated BLAST to search for 4.2.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385Y3C8 at UniProt or InterPro

Protein Sequence (734 amino acids)

>DZA65_RS22415 right-handed parallel beta-helix repeat-containing protein (Dickeya dianthicola ME23)
MKYAVSGLISVALNSLLLLGSNTTFAATQDAAPVWRGIAFGQSTDVNFATNVLPNKVGVN
DVTINGKKLTVNDKVDLSAPITIESRGGKIANTHDGLTFFYTQLPANVNFTLQSDVTVDQ
FGPESDAKPNAQEGAGLLVRDILGVPRQEPLKEGYEEFPAASNMVMNAIMTQDKKSKTEV
KMQLISRDGVTQPWGNTNAEITRASYQEKINLEQTPTFRLKLERTDDGFITSYAPKGSDQ
WVSKTEKGADLVTRQDKDHYYVGFFASRNVKITISNASLTTSPANTKPSTPFKAEANAPL
LQVASSPLSASDTYPVQARVNYNGTVEVFQNGKSLGKPQQIRAGNYFSLTAKLTQPKSDF
KLIYVPGEGEDKTAKETSFSVAKIKLADAKKLYVSPDGKADNNGSKDAPLDIKTAINALQ
TGGTLWLMDGDYSATVIPVSASGNANGIKTLMPVGKKAVFHGLQLNASYWKVKGIEITEK
SFRIEGSRNQIEQVLAHHCDNTGIQVSSNDSVGRPLWASHNLILNSESHSNQDPSKKDAD
GFAVKMRVGEGNVIRGAFSHDNVDDGFDLFNKIEDGPNGVVVIENSISVNNTSNGFKLGG
EGQPVAHQVKNSIAIGNHMDGFSDNFNPGALQVSNNIALDNVRFNFIFRPSPYYGPEKQG
IFKNNVSLRTHTGKYDDAVVGRVDVSNYFIKNNRALNSQGKEITTANYKSVAVPAVFSRD
EKGNLQLGDFLKKK