Protein Info for DZA65_RS22225 in Dickeya dianthicola ME23

Annotation: Der GTPase-activating protein YihI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 177 PF04220: YihI" amino acids 14 to 168 (155 residues), 191.3 bits, see alignment E=4.5e-61

Best Hits

Swiss-Prot: 61% identical to YIHI_PECAS: Der GTPase-activating protein YihI (yihI) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K09894, hypothetical protein (inferred from 87% identity to ddd:Dda3937_01114)

Predicted SEED Role

"Protein of unknown function DUF414" in subsystem Experimental tye

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CUC7 at UniProt or InterPro

Protein Sequence (177 amino acids)

>DZA65_RS22225 Der GTPase-activating protein YihI (Dickeya dianthicola ME23)
MKQPSKGAGHKASAPKIKRKNREQLDLEARERKRQKKHRGHAAGSRAQASGGDQHNASSG
KTKDPRIGSKKPVSLLPEGAAVVVKAPVASQEKPVRLPPQEELEMLENDPRLDALLDRLE
KGETLPAKEQSWLDETLDRIDILMEQLGISLDDDEEDEEQEEDMLQLLRRNNPKDNH