Protein Info for DZA65_RS22035 in Dickeya dianthicola ME23

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 PF00005: ABC_tran" amino acids 19 to 161 (143 residues), 130.1 bits, see alignment E=8.9e-42 PF08402: TOBE_2" amino acids 270 to 341 (72 residues), 36.2 bits, see alignment E=5.3e-13

Best Hits

Swiss-Prot: 48% identical to UGPC_RHILO: sn-glycerol-3-phosphate import ATP-binding protein UgpC (ugpC) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)

KEGG orthology group: K02023, multiple sugar transport system ATP-binding protein (inferred from 92% identity to ddd:Dda3937_01153)

Predicted SEED Role

"Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1)" in subsystem Polyamine Metabolism (TC 3.A.1.11.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385Y359 at UniProt or InterPro

Protein Sequence (367 amino acids)

>DZA65_RS22035 ABC transporter ATP-binding protein (Dickeya dianthicola ME23)
MAEIVLDGVTKAWGDTPVLHPVNLTLADGEFVAILGPSGCGKSTTLFLLAGLYAPTQGHI
LFDGQRVNGVDARDRNVGVVFQSYALYPHLSVYDNIAFPLRFKPGERAGRDQQVREAAAL
VQVTELLDRKPSALSGGQQQRVALARALVKRPSLLLLDEPLSNLDATLRMTMRTELKAIH
ARSRATTLMVTHDQLEAMTLASRIICMNQGRVEQTGTPQQLYRQPANTFVAGFIGSPPIC
LLPGQASGYQLTVGETRWGLSSMYHGALTLGIRPEDVALTPPGVGSLFGRIEHIEPMGRE
ILYRLYTPLGPLQALVAGSTAQYDAGMCVGVSLSAETLLLFGADGNRLADVGVVLSADVF
SACRTAG