Protein Info for DZA65_RS21845 in Dickeya dianthicola ME23

Annotation: insulinase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF00675: Peptidase_M16" amino acids 51 to 158 (108 residues), 38.6 bits, see alignment E=1e-13 PF05193: Peptidase_M16_C" amino acids 199 to 376 (178 residues), 61.1 bits, see alignment E=1.4e-20

Best Hits

Swiss-Prot: 58% identical to YHJJ_SALTY: Protein YhjJ (yhjJ) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 98% identity to ddd:Dda3937_01996)

Predicted SEED Role

"Protein YhjJ, putative peptidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4DAH3 at UniProt or InterPro

Protein Sequence (485 amino acids)

>DZA65_RS21845 insulinase family protein (Dickeya dianthicola ME23)
MQGTKFGLFVGGVLLAAAVGNVQAEALQPDPAWQQGKLDNGFSWQLLATPQRPSDRIELR
LMINTGSLTENAQQTGFSHFISRLALLPRDTFSAGQLPSLWQQSESETRPLPPATTSYDF
TSYNLSLPNNRPDLLKDALSWLADTAGQLQINDKRIASATKMIDPVATAPTNPQDPSWRY
RLKGSSLLSYAPGQPLKASVNAEQLSKYYKTWYTPDAMTLYVVGNVDSRAIGEQIDRVFS
PLQGKRVAPSPLPTLSAMPSAPISLMDSSVKQDILSLVWDMPWQPIRDSQALARYWHSDL
AREALFWHMQQVLTKSPLKDTNVRFDCNVVYGRAQCAIHLDNVTSESAQAGVTFLSKELL
ALRDKGLSQAEFDTLMARKTEELSKLFATYARASTDILMDQRLRSQKNGVVDIAPEQYQK
LRQNYLSSVTLEMLNQELHQQLSQEATLVMLQPQGEPEANMKALRETYMSIMQPDNNAAS
VAPAQ