Protein Info for DZA65_RS21665 in Dickeya dianthicola ME23

Annotation: sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 439 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF01547: SBP_bac_1" amino acids 38 to 338 (301 residues), 121 bits, see alignment E=1.1e-38 PF13416: SBP_bac_8" amino acids 46 to 359 (314 residues), 129.7 bits, see alignment E=1.9e-41

Best Hits

Swiss-Prot: 85% identical to UGPB_PECAS: sn-glycerol-3-phosphate-binding periplasmic protein UgpB (ugpB) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K05813, sn-glycerol 3-phosphate transport system substrate-binding protein (inferred from 99% identity to ddd:Dda3937_02029)

MetaCyc: 83% identical to sn-glycerol 3-phosphate ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-34-RXN [EC: 7.6.2.10]; 7.6.2.10 [EC: 7.6.2.10]

Predicted SEED Role

"Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein (TC 3.A.1.1.3)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization (TC 3.A.1.1.3)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CGL1 at UniProt or InterPro

Protein Sequence (439 amino acids)

>DZA65_RS21665 sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB (Dickeya dianthicola ME23)
MFQHAIRKTAAVVIMALAASAQAQAVTEIPFWHSMEGELGKTVNSLADRFNQTHSDVNIV
PVYKGNYEQSLAAGIAAFRSGNAPAILQVYEVGTATMMTSKAIKPVYQVFKDAGVPYDEN
IFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQQMAEYTAK
LRASGMKCGYASGWQGWIQIENFSAWNGLPIATKNNGFDGLDAVLEFNKPVQVKHIQMLE
DMNKKGDFTYYGRKDEPTEKFYNGDCAMTTASSGSLANIRQYAKFNYGVAMMPYDADVKG
APQNAIIGGASLWVMNGKDAATYKGVAEFMQFLSTPEIAAEWHQKTGYLPITTAAYELTK
QQGFYDKNPGADIATRQMLNKEPLPFTKGLRLGNMPQIRTIVDEELESVWTGKKTPQQAL
DAAVERGNALLRRFEQANK