Protein Info for DZA65_RS21040 in Dickeya dianthicola ME23

Annotation: threonine export protein RhtC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 207 signal peptide" amino acids 6 to 6 (1 residues), see Phobius details transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 38 to 63 (26 residues), see Phobius details amino acids 69 to 90 (22 residues), see Phobius details amino acids 126 to 141 (16 residues), see Phobius details amino acids 152 to 175 (24 residues), see Phobius details amino acids 186 to 205 (20 residues), see Phobius details PF01810: LysE" amino acids 14 to 206 (193 residues), 187 bits, see alignment E=1.4e-59 TIGR00949: homoserine/Threonine efflux protein" amino acids 18 to 203 (186 residues), 208.4 bits, see alignment E=3.9e-66

Best Hits

Swiss-Prot: 73% identical to RHTC_ECOLI: Threonine efflux protein (rhtC) from Escherichia coli (strain K12)

KEGG orthology group: K05835, threonine efflux protein (inferred from 96% identity to dze:Dd1591_0194)

MetaCyc: 73% identical to L-threonine exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-0244

Predicted SEED Role

"L-lysine permease" in subsystem Lysine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4D6G9 at UniProt or InterPro

Protein Sequence (207 amino acids)

>DZA65_RS21040 threonine export protein RhtC (Dickeya dianthicola ME23)
MLMLFLTVALVHWIALMSPGPDFFFVSQTAISRSRREALMGVLGITLGVLVWAAIALMGL
HLLLERMAWLHRLVTIGGGLYLCWMGWQLLRSALRKRAHQGEETVEAALPQQGKTFMRGL
LTNLSNPKALIYFGSVFSLFVGDDVGAAARWGLFALISLETLLWFSLVALVFALPVMRRG
YQRLAKWVDGLAGALFTGFGIHLIISR