Protein Info for DZA65_RS19460 in Dickeya dianthicola ME23

Annotation: molybdopterin adenylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00177: molybdenum cofactor synthesis domain
  • amino acids 6 to 145 (140 residues), 132.3 bits, E=6.6e-43
• PF00994: MoCF_biosynth
  • amino acids 8 to 145 (138 residues), 90.4 bits, E=4.6e-30

Best Hits

Swiss-Prot: 84% identical to MOG_SHIFL: Molybdopterin adenylyltransferase (mog) from Shigella flexneri

KEGG orthology group: K03831, molybdopterin adenylyltransferase (inferred from 97% identity to ddd:Dda3937_00388)

MetaCyc: 84% identical to molybdopterin adenylyltransferase (Escherichia coli K-12 substr. MG1655)
RXN-8344 [EC: 2.7.7.75]

Predicted SEED Role

"Molybdopterin biosynthesis molybdochelatase MogA"

MetaCyc Pathways

• molybdenum cofactor biosynthesis (3/3 steps found)
• bis(tungstenpterin) cofactor biosynthesis (1/4 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.75

Sequence Analysis Tools

See A0A3A4D239 at UniProt or InterPro

Protein Sequence (195 amino acids)

>DZA65_RS19460 molybdopterin adenylyltransferase (Dickeya dianthicola ME23)
MNSLCVGLVSISDRASSGVYQDEGIPALQAWLAEALTTPFDVQTRLVPDEQPLIEQTLCE
LVDECGCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLRFVPTAILSRQV
GVIRKQALILNLPGQPKSIRETLSGLKDASGQVMVPGIFASVPYCIQLLEGPYIETNPDV
VAAFRPKSAIRNIKN