Protein Info for DZA65_RS19245 in Dickeya dianthicola ME23

Annotation: HTH-type transcriptional regulator SgrR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 555 PF12793: SgrR_N" amino acids 5 to 118 (114 residues), 137.8 bits, see alignment E=1.9e-44 PF00496: SBP_bac_5" amino acids 164 to 308 (145 residues), 73.8 bits, see alignment E=1.5e-24

Best Hits

Swiss-Prot: 71% identical to SGRR_PECAS: HTH-type transcriptional regulator SgrR (sgrR) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K11925, SgrR family transcriptional regulator (inferred from 96% identity to ddd:Dda3937_01356)

Predicted SEED Role

"SgrR, sugar-phosphate stress, transcriptional activator of SgrS small RNA" in subsystem Sugar-phosphate stress regulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CI74 at UniProt or InterPro

Protein Sequence (555 amino acids)

>DZA65_RS19245 HTH-type transcriptional regulator SgrR (Dickeya dianthicola ME23)
MSSPRLQQQFIRLWQCLQGQDTNTTLQELALLLNCSRRHIRSLLNAMQQQGWLTWQAEAG
RGKRSRLGFLYTGLTLQQQRAEDLLEQDRIDQLVQLVGDKETVRQMLLSHLGRSVRQGRH
LLRILYYRPMHNLLPGSALRRSETHIARQIFSGLTSLNEENGELLPDIAHHWQALSPLHW
RFYLRPAIRFHHGRELTLEDVIASLSRLTALPLFSHLTDISSPTPFVLDIRLSMPDDWLP
WLLGSVPAMILPKEWQTLPDFMRQPIGTGPYQVVRNSPNQLKINAFDDYFGYRALIDEVS
IWVLPDAPIIPACTVTLQGDDTTDNELENRLEEGCYFLLFDRRSPQMADPDIRHWLCQVL
SPVAMLGLADTPYQSDWSPAYGLLPRWHHSPPRAVREKPVGLTHLTLTGYRDHPEYAVIS
SIMGRLLASHGVTLTLRSLEFDDWREGSDASDLWLGSANFYLPLEFSLFAMLYELPLLRH
CLGDDELEHTARQWRQGELSLAEWCQSLVSRQQLHPLFHHWLRLQGQANMRGLRMNTLGW
FDFKSAWFAPPTPTA