Protein Info for DZA65_RS17480 in Dickeya dianthicola ME23

Annotation: catalase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00199: Catalase
  • amino acids 35 to 412 (378 residues), 558 bits, E=1.2e-171
• PF06628: Catalase-rel
  • amino acids 437 to 497 (61 residues), 48.3 bits, E=9.1e-17

Best Hits

Swiss-Prot: 80% identical to CATB_PSEAE: Catalase (katB) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 97% identity to ddd:Dda3937_03164)

MetaCyc: 46% identical to catalase monomer (Homo sapiens)
Catalase. [EC: 1.11.1.21, 1.11.1.6]; 1.11.1.6 [EC: 1.11.1.21, 1.11.1.6]

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• ethanol degradation IV (3/3 steps found)
• superoxide radicals degradation (2/2 steps found)
• methanol oxidation to formaldehyde IV (1/2 steps found)

KEGG Metabolic Maps

• Methane metabolism
• Tryptophan metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.21 or 1.11.1.6

Sequence Analysis Tools

See A0A3A4D754 at UniProt or InterPro

Protein Sequence (515 amino acids)

>DZA65_RS17480 catalase (Dickeya dianthicola ME23)
MSNHAAIHRVPGWQKPLVIVSSLLMAYPAMADILTRDNGTPVGDNQNSQTAGPNGPVLLQ
DVQLLQKLQRFDRERIPERVVHARGTGAHGKFTPTEDISDLTIAEVFKKGSETPVFVRFS
SVVHGNHSPETLRDPRGFATKFYTTQGNWDLVGNNFPTFFIRDAIKFPDMVHAFKPDPRT
NQDNDGRRFDFFSHVPESIRTLTLLYSNEGTPVSYRNMDGNGVHAYKLVNAKGEVHYVKF
HWKTLQGVKNLDPKQVDEVQGKDYSHMTNDLVAAITRGDYPKWDLYIQVLTPDDLAKFDF
NPLDATKIWPGVPERKIGQMVLNKNPDNFFQETEQVAMAPANLVPGIEASEDRLLQGRLF
SYADTQMYRLGANGLSLPINAPLKKANNINQDGSLNGGHTQDKGVNYQPSRLYPREELAS
ARYSQTPLSGTTQQRKIQKEQNFKQTGELYRSYNKKDQDDLVQSLGSALAMADTESKTIM
LSYFYKADATYGTRLTDVAKGDLSKVQSLASKLAD