Protein Info for DZA65_RS17175 in Dickeya dianthicola ME23

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 307 PF00005: ABC_tran" amino acids 21 to 165 (145 residues), 117.4 bits, see alignment E=7.6e-38 PF13304: AAA_21" amino acids 137 to 194 (58 residues), 31.1 bits, see alignment E=2.4e-11

Best Hits

Swiss-Prot: 84% identical to YADG_ECOLI: Uncharacterized ABC transporter ATP-binding protein YadG (yadG) from Escherichia coli (strain K12)

KEGG orthology group: K09687, antibiotic transport system ATP-binding protein (inferred from 98% identity to ddd:Dda3937_04074)

Predicted SEED Role

"ABC-type multidrug transport system, ATPase component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385Y0R2 at UniProt or InterPro

Protein Sequence (307 amino acids)

>DZA65_RS17175 ABC transporter ATP-binding protein (Dickeya dianthicola ME23)
MTYALELANVTKTYPGGVRALRGIDLRVEAGDFYALLGPNGAGKSTTIGIISSLVNKTDG
RIQVFGHDLDRDIVNAKRQLGLVPQEFNFNPFETVMQIVVNQAGYYGVPRQEALRRAEKY
LNQLDLWGKRNERALMLSGGMKRRLMIARALMHEPRLLILDEPTAGVDIELRRSMWGFLK
ALNGQGTTIILTTHYLEEAEMLCRNIGIIQSGQLVENTSMKALLAKLQSETFFFDLAAKS
ALPRLEGYQHRLVDTSTLEVEVKREQGLNGIFSQLSAQGIQVLSMRNKANRLEELFVALL
NNNGDKA