Protein Info for DZA65_RS16890 in Dickeya dianthicola ME23

Annotation: DNA repair protein RecO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 244 PF11967: RecO_N" amino acids 4 to 76 (73 residues), 74.2 bits, see alignment E=6.8e-25 TIGR00613: DNA repair protein RecO" amino acids 5 to 230 (226 residues), 137.4 bits, see alignment E=2.6e-44 PF02565: RecO_C" amino acids 86 to 226 (141 residues), 72.5 bits, see alignment E=3.4e-24

Best Hits

Swiss-Prot: 85% identical to RECO_PECAS: DNA repair protein RecO (recO) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K03584, DNA repair protein RecO (recombination protein O) (inferred from 100% identity to ddd:Dda3937_03852)

MetaCyc: 80% identical to recombination mediator protein RecO (Escherichia coli K-12 substr. MG1655)
RXN0-2606

Predicted SEED Role

"DNA recombination and repair protein RecO" in subsystem DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4DE01 at UniProt or InterPro

Protein Sequence (244 amino acids)

>DZA65_RS16890 DNA repair protein RecO (Dickeya dianthicola ME23)
MEGWQRAFVLHGRPYSETSLLLDLFSENEGRVRVLAKGARARRSSLKGALQPFTPLLVRW
GGRGEVKTLRNAEPVSLALPLSGPLLYSGLYVNELLTRVLELETDYSALFFDYLYCLQQL
AAASGSPEPALRRFELALLEHLGYGVDFLHCAGSGEPVADTMTYRYRAEKGFIASLVVDN
VSFTGRELQALASREFPDIDTLRAAKRFTRMALKPYLGGKPLKSRELFRQFIPKPYKAAP
DGKI