Protein Info for DZA65_RS16800 in Dickeya dianthicola ME23

Annotation: pectin acetylesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 551 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF00657: Lipase_GDSL" amino acids 283 to 526 (244 residues), 27.8 bits, see alignment E=2.6e-10 PF13472: Lipase_GDSL_2" amino acids 283 to 523 (241 residues), 35 bits, see alignment E=2.2e-12

Best Hits

KEGG orthology group: None (inferred from 93% identity to dze:Dd1591_1088)

Predicted SEED Role

"rhamnogalacturonan acetylesterase" in subsystem L-rhamnose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385Y0C5 at UniProt or InterPro

Protein Sequence (551 amino acids)

>DZA65_RS16800 pectin acetylesterase (Dickeya dianthicola ME23)
MLTTTWKRTLFLGSLLCLPLSFAQAESTAPEVPVAPSQPTLNVATLAPNTLISGRVAYRD
IRFPATLLIKDQRGVQRNVKTDIQGRFYADVSSLVAPLRLSAIEAGGQHCLASNQLRAVC
LSALVPQLRDGHENHININPLTDRILSDVAASAGYIGPQQLIDAAVLPALSATAWETAYR
EFHAGFDDALKQAGIAVPTQFDPLTYPDTLTPAFTQVLQVINHARNYHNDSGQAGHTVLT
DIVFRPIIGLNASGSYEPLDLTSANQHRKALEQARTRIFIVSDSTAATYEKARFPRMGWG
QVFEQQFRPGSHIAVVNGARSGRSSRDFYYEGWFRQMEPFMRPGDYLFIGMGHNDQNCDS
QKAVRGAADVANLCTYPNSADGKPQYPQGKPDMSFQISLERYIRYARAHRMIPVLLTPTA
RVKNAEGKNGTPAVHSHLTKQNKAGGYAFIGDYTQTIRDTASKNKVPLLDVETATLALAN
QGDGQQWQQYWLAVDPERYPYYRDQAGSLTQPDTTHFQQKGAQAVAVIVADQINATPSLR
ELAGKLQPADR