Protein Info for DZA65_RS16760 in Dickeya dianthicola ME23

Annotation: nickel/cobalt transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 69 to 90 (22 residues), see Phobius details amino acids 111 to 134 (24 residues), see Phobius details amino acids 150 to 168 (19 residues), see Phobius details amino acids 233 to 254 (22 residues), see Phobius details amino acids 260 to 288 (29 residues), see Phobius details amino acids 309 to 331 (23 residues), see Phobius details PF03824: NicO" amino acids 70 to 330 (261 residues), 119 bits, see alignment E=1.3e-38

Best Hits

KEGG orthology group: None (inferred from 80% identity to ddc:Dd586_3078)

Predicted SEED Role

"putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385Y145 at UniProt or InterPro

Protein Sequence (346 amino acids)

>DZA65_RS16760 nickel/cobalt transporter (Dickeya dianthicola ME23)
MPVNRSHVTRNYLRWWPLALFLLLMGAAVWQAMVWWPSILLQSIEWQRSLHQQMADLMEQ
VRAQPHQAGWTLVMFSLAYGVLHAVGPGHGKVVIATYLATHPSRLKGSLQLTFASALLQG
MVAIVLVTLVLAVLQLSSRALHIGSYWMEKSSFVLVAGLGGWLCLRGFRRLRALRFTRVK
PRIRSLTLRDASASGIRLTPVVRHQHDDNCGCGHQHVPAAEALNHSDGWRTRLMVVLAMG
LRPCSGAILVLLFAKVLDVFVWGVISALVMALGTALTVSLLGVAVLFCRRQLERLSRAGA
FSSPRWQPLVWSALSLAGGMTLTFVGIVLYLTTQPDVMSGIRPVLG