Protein Info for DZA65_RS15860 in Dickeya dianthicola ME23

Annotation: ATP-binding cassette domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 PF00005: ABC_tran" amino acids 24 to 183 (160 residues), 120.7 bits, see alignment E=7.3e-39

Best Hits

Swiss-Prot: 59% identical to NOCP_AGRFC: Nopaline permease ATP-binding protein P (nocP) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K10021, octopine/nopaline transport system ATP-binding protein [EC: 3.6.3.-] (inferred from 95% identity to ddd:Dda3937_01668)

MetaCyc: 53% identical to cystine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1)" in subsystem Arginine and Ornithine Degradation (TC 3.A.1.3.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.- or 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CNH6 at UniProt or InterPro

Protein Sequence (260 amino acids)

>DZA65_RS15860 ATP-binding cassette domain-containing protein (Dickeya dianthicola ME23)
MNKTAPITLSMIDIRKSFGTLEVLNGISLDARRGEVISLLGASGSGKSTFLRCINLLETP
DAGTVAVSGEMILMKRHKLGYQVAADRRQVERLRTRLGMVFQNFNLWSHMTVLQNVIEGP
LHILRRSRAECVGQAEALLAKVGLYERRHFYPTQLSGGQQQRVAIARALSMEPEVMLFDE
PTSALDPELVGDVLKVMRGLAEEGRTMLVVTHEMGFARHVSSRVVFMHQGRIDCEGAPDA
MFAGDSSPRFQQFIASHQTV