Protein Info for DZA65_RS15820 in Dickeya dianthicola ME23

Annotation: MHS family MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 61 to 84 (24 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 120 to 141 (22 residues), see Phobius details amino acids 162 to 187 (26 residues), see Phobius details amino acids 194 to 215 (22 residues), see Phobius details amino acids 259 to 282 (24 residues), see Phobius details amino acids 294 to 312 (19 residues), see Phobius details amino acids 320 to 341 (22 residues), see Phobius details amino acids 347 to 368 (22 residues), see Phobius details amino acids 388 to 408 (21 residues), see Phobius details amino acids 414 to 435 (22 residues), see Phobius details PF07690: MFS_1" amino acids 28 to 388 (361 residues), 95.6 bits, see alignment E=3e-31 amino acids 273 to 438 (166 residues), 34.8 bits, see alignment E=9e-13 PF00083: Sugar_tr" amino acids 69 to 444 (376 residues), 80.6 bits, see alignment E=1.2e-26

Best Hits

Swiss-Prot: 76% identical to YDFJ_ECOLI: Putative transporter YdfJ (ydfJ) from Escherichia coli (strain K12)

KEGG orthology group: K08173, MFS transporter, MHS family, metabolite:H+ symporter (inferred from 90% identity to dze:Dd1591_1268)

Predicted SEED Role

"Putative transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4DJ17 at UniProt or InterPro

Protein Sequence (470 amino acids)

>DZA65_RS15820 MHS family MFS transporter (Dickeya dianthicola ME23)
MNKAKTTFVPGKTERNSSDLVKAAISGWLGTALEFMDFQLYSLGAALVFHEIFFPEQSAT
IALILAMGTYGAGYIARIIGAFVFGRMGDAIGRKKVLFITITMMGVCTTLIGVLPTYAQI
GIFAPLLLVMLRIIQGLGAGAEISGAGTMLAEYAPRGKRGIISSLVAMGTNCGTLSATGI
WATMFFLLDREQLLAWGWRIPFLASAIVMVFAIWLRMNLKESPVFEQVSETPADANTVMT
SQHKSLTAMLGSKSFWLATGLRFGQAGNSGLIQTFLAGYLVQSLLFEKRIPTDALMLSSI
IGFITIPLLGWLSDKFGRRLPYIIMNISAMLLAYPTLSIIVNKDMGVSAIIAGIIIIHNI
AVLGLFALENITLAELFGSRNRFTQMAIAKEAGGLIAVGLGPVLAGIFCNMVGSWWPIVV
MLIIYSCIGLFTAIAMPEVKDRDLSAPEDATDIHTARHAIISSQDQYRGF