Protein Info for DZA65_RS15810 in Dickeya dianthicola ME23

Annotation: D-galactonate dehydratase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 PF02746: MR_MLE_N" amino acids 13 to 110 (98 residues), 116.1 bits, see alignment E=1.1e-37 PF13378: MR_MLE_C" amino acids 137 to 379 (243 residues), 155.4 bits, see alignment E=1.8e-49

Best Hits

Swiss-Prot: 92% identical to MAND_SALG2: D-galactonate dehydratase family member RspA (rspA) from Salmonella gallinarum (strain 287/91 / NCTC 13346)

KEGG orthology group: K08323, starvation sensing protein RspA (inferred from 97% identity to ddc:Dd586_2939)

Predicted SEED Role

"Starvation sensing protein RspA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CJV6 at UniProt or InterPro

Protein Sequence (404 amino acids)

>DZA65_RS15810 D-galactonate dehydratase family protein (Dickeya dianthicola ME23)
MKIVSAEVFVTCPGRNFVTLKITTASGVTGIGDATLNGRELSVASYLKDHLCPQLIGRDA
RQIEDIWQYFYKGAYWRRGPVTMSAISAVDMALWDIKGKAANMPLYQLLGGASRAGVMVY
CHTTGHSIDEVLEDYARHRDQGFKAIRVQCGIPGMKTTYGMAKGQGLAYEPATKGNWPEE
QIWSTEKYLDFMPNLFEAVRNKFGFNEHLLHDMHHRLTPIEAARFGKSVEPYRLFWMEDP
TPAENQACFRLIRQHTVTPIAVGEVFNSIWDCKQLIEEQLIDYIRTTITHAGGITGMRRI
ADFASLYQVRTGSHGPSDLSPACMAAALHFDLWVPNFGIQEFMGYSEQMLEVFPHNWTFE
DGYMHPGDKPGLGIEFDEKLAAKYPYEPANLPIARLEDGTLWNW