Protein Info for DZA65_RS15715 in Dickeya dianthicola ME23

Annotation: mechanosensitive ion channel family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 814 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 215 to 237 (23 residues), see Phobius details amino acids 258 to 278 (21 residues), see Phobius details amino acids 298 to 317 (20 residues), see Phobius details amino acids 337 to 357 (21 residues), see Phobius details amino acids 363 to 388 (26 residues), see Phobius details amino acids 412 to 434 (23 residues), see Phobius details amino acids 445 to 469 (25 residues), see Phobius details amino acids 494 to 515 (22 residues), see Phobius details amino acids 543 to 563 (21 residues), see Phobius details amino acids 586 to 609 (24 residues), see Phobius details amino acids 615 to 634 (20 residues), see Phobius details PF12607: DUF3772" amino acids 142 to 202 (61 residues), 63.3 bits, see alignment 2.1e-21 PF21088: MS_channel_1st" amino acids 594 to 631 (38 residues), 25.9 bits, see alignment 1.2e-09 PF00924: MS_channel_2nd" amino acids 633 to 698 (66 residues), 75.8 bits, see alignment E=3.6e-25

Best Hits

KEGG orthology group: None (inferred from 97% identity to ddd:Dda3937_02408)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385Y043 at UniProt or InterPro

Protein Sequence (814 amino acids)

>DZA65_RS15715 mechanosensitive ion channel family protein (Dickeya dianthicola ME23)
MRKGLLGIYGWMLLVALFAFSSVSMAATDPAPGGQEESAEKVNVDTELVKLQKQLDGIKQ
QISGTTTDAKLSVLNDTTLELVANADKLAGVLTPMRAQLQAQLDVLGPAPQPQAAVSETA
EVTRKRATLNQQKQKLDTQASQVQAIKTGAENLSTQILALRRNALKNQLALNSGSMLGSR
FWSPIIKPVQEDIDRLSDLKDDLTEAFVAAWQPGWRYGSAFFLLLAVALSTAGRKLLEKY
LARAGIHLLPEGRLRRSFLAIAVVLSTVLMMGMAVLLVDYVFTRHGDVTDRAAGFMENLV
RLVVFCSMISGLGRAFLSNKRPSWRLPAIANPVARAMEPFSIIATGFIVVFGVIEQINTT
SGISVGVTIVGNGLSSLFLALTSGAIALRSNQIRRRMVEAGETPEARSTLSGLIHLAVLL
TTLAVLVSLLIGYISLARFLTYELVWVGMVLSLLYLSTTFVEDVCESLFSPAFASGRQIK
RTLNLDDRHLDQAAAILSAGLKVLLILMAVVALLNGTFGSTTPVDLVQKAVEIWGGKGLE
SISIVPAHLVNAVVLLVIGIYSLRVSRRWLEHEFFPKTTLEAGIKASLVTLYSNIGYILI
ILLTLATLGIEWSKLAWIVSALSVGIGFGLQEIVKNFISGLILLTERPVKVGDLVNISGV
EGDIRRINVRATEIQLGDRSTVIVPNSQFISQNVRNITMGNPQGVATLALTFPLDIDPDV
VKNILLDAYHAHEKILETPVPSVMFSQLTPNGMVLSVTGYVGSPRMVASAKSDLLFDIIK
RLRTASIPLAVPQKMVLESNVDVAALQADAVPRQ