Protein Info for DZA65_RS14990 in Dickeya dianthicola ME23

Annotation: transcriptional regulator LrhA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 transmembrane" amino acids 18 to 36 (19 residues), see Phobius details PF00126: HTH_1" amino acids 13 to 71 (59 residues), 64 bits, see alignment E=1e-21 PF03466: LysR_substrate" amino acids 97 to 275 (179 residues), 92.9 bits, see alignment E=1.9e-30

Best Hits

Swiss-Prot: 96% identical to PECT_DICD3: HTH-type transcriptional regulator PecT (pecT) from Dickeya dadantii (strain 3937)

KEGG orthology group: None (inferred from 96% identity to ddd:Dda3937_00364)

Predicted SEED Role

"LysR family transcriptional regulator lrhA" in subsystem DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XZE2 at UniProt or InterPro

Protein Sequence (316 amino acids)

>DZA65_RS14990 transcriptional regulator LrhA (Dickeya dianthicola ME23)
MTNTSRPVLNLDLDLLRTFVAVADLNTFAAAAVAVCRTQSAVSQQMQRLEQLIGKELFAR
HGRNKLLTEHGIQFLGYARKILQFNDEACASLMYSDIQGTLTIGASDDTADTILPFILQR
VTAVFPKLSIAVSIKRSAEMADMLQQGKIDLVITTTNNDDLPHVLLRTSPTLWYCSADYQ
YQPGETVSLVVLDEPSPFRTLALDQLTAAGIPWKTSYVASTLSAVRAAVKAGLGITVRSV
EMMSPELRVLGEEEGLPKLPDTRYYLCRNPEHDNELTNAIFSAIESGTRSHLLPVSIGTE
NDTREPPTDKSLKDIT