Protein Info for DZA65_RS14425 in Dickeya dianthicola ME23
Annotation: TrbI/VirB10 family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K03195, type IV secretion system protein VirB10 (inferred from 72% identity to ddc:Dd586_1453)Predicted SEED Role
"Inner membrane protein forms channel for type IV secretion of T-DNA complex (VirB10)" in subsystem Type 4 secretion and conjugative transfer
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A3A4C408 at UniProt or InterPro
Protein Sequence (413 amino acids)
>DZA65_RS14425 TrbI/VirB10 family protein (Dickeya dianthicola ME23) MTDKPIPETTEKTVADLEAEARERARSAMASQAPEQNTPPGQPKVTRFKKASSRRTLLVS LLSLGALIALALGGDRFLVALKQSNDKSVETPAPPSASTGQHERKNLGMDNNPFGLFGQD KQETATDNPPIQTAPSSEPPALNKAAALVDGSSSAADSTQRGNTQASQTAPSGTQHNQSN QSKDAPATTSGTEANNANPGVAKVTSVRRLGLDPNLYLPVDRYVPCSMMRRFVSDVGGRI SCLIGEDVYSANHYVKLLPAGTVARGFYRTGALQHGRSRMFVIWTELRTPEPGSLQIPLI DTEVTGPLGEAGISGWIDTHFWERFGNALMLSTVQDVAAAASDSAPGKDRNTDYTENTRA AASEMAKTALENSINIPPTMYLNQGDVIGIMTGTDIDFSSVYQLRLKKRWYER